Posted by medlib on December 8, 2002, at 23:09:08
In reply to Can't Sleep Normally -- New Meds?, posted by Simcha on December 8, 2002, at 5:38:58
Hi Simcha--
Yeah, taking 6 drugs is a logistical hassle, and the chances for drug interactions rise with the number of meds involved.
2 of your psych meds can cause insomnia: Wellbutrin does in over 40% of those taking 300 mg. XL. Celexa can cause insomnia in some, drowsiness in others; *and* it can cause respiratory problems--coughing, frequently; asthma, rarely. Neurontin is not metabolized in the body at all; it is excreted in the urine unchanged.
You're not taking a lot of Flonase, but it *can* interact with Celexa. Flonase inhibits the liver enzyme CYP3A4, which is one of the 2 which metabolize (break down) Celexa. The result is that Celexa can stay in the bloodstream longer and its effect may be stronger.
You may want to consider switching the Celexa to a different SSRI. Even better, the doc who prescribed your asthma meds should talk to your pdoc; maybe, both need to talk to a pharmacist.
I get a little annoyed when no one will take responsibility for the whole patient. I *don't* have medical insurance, and I'm likely not to pay a doc who won't take the time to read his PDR or consult an Internet drug database. I most certainly will not go back. End of rant (for now).
Take care (and a pinch of paranoia re meds wouldn't hurt)---medlib
poster:medlib
thread:130984
URL: http://www.dr-bob.org/babble/20021203/msgs/131055.html