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SSRI's and dopamine depletion

Posted by k on November 30, 2002, at 10:53:06

Hey all..
It seems that when people take Serotonin reuptake inhibitors, they actually begin to deplete the dopamine in their brains... some doctors say this is the reason people build up tolerances to SSRI's.

This seems very serious to me. Dopamine is one of the most important chemicals in the brain. It has a role in Parkinson's disease.. as well as major roles in brain chemistry regulation.
The thing that gets to me is that the withdrawals, and some of the side effects, are heavy duty neural physical (shakes, zaps, etc.). When I went through my withdrawals, the thing that scared me the most was the idea that I may have done serious and long lasting damage to my brain. This connection between SSRIs and dopamine is something I have just discoverd.
Does anyone know more about this? This is damn serious.....


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