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SSRI Poop-Out

Posted by Fee on November 20, 2002, at 20:10:28

I have been taking Sertraline (zoloft) for over ten years and have had two major episodes of depresson in the last year - am still in one. Why has this happened??? Has the drug 'pooped out' ? My doctor increased the dose from 100mg daily to 200mg daily. This did nothing at all. He then supplemented this with Mirtazapine, starting off on low doses and increasing until finally i started to feel some small improvement. I am now on 90mg daily of mirtazapine which is apparently a very high dose - as well as the sertraline, and I am only feeling a slight improvement. Most days are hell on earth. Will I ever get better? When a drug stops working in your system, does that mean that nothing will cure me? Or would a different anti depressant help? Should I be asking my GP to switch my meds to something new? Has anyone ever experienced this? Please tell me that it's not the end of the road for me- I couldn't go on living if I thought it was always going to be like this.
Love and light
Fee


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poster:Fee thread:128540
URL: http://www.dr-bob.org/babble/20021116/msgs/128540.html