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Re: What is rationale behind adding sedative AD? » AnneL

Posted by Ritch on October 20, 2002, at 16:12:56

In reply to What is rationale behind adding sedative AD? » AnneL, posted by AnneL on October 20, 2002, at 13:27:01

> Hi Ritch,
> OK I have bounced from I am depressed to I am getting off of meds to I am depressed or I am having a side effect of Effexor/Klonopin combo
> (long half life of Klonopin causing fatigue, Effexor causing SSRI/SNRI apathy if this is a credible side effect). I am not trying to put you on the spot, but just am very curious as to why you suggest a sedating augmentation strategy with Remeron, Elavil or Pamelor. Aren't I getting enough sedation with the Klonopin? It certainly makes for one to dread having to get up for work in the morning! Any ideas you or other fellow babblers may have to help me get going? Thank you so much! Anne :)

Hi, you've got some interesting questions. The main thing I got from your original post was that you were experiencing some bad insomnia and that you were still depressed (hence the sedative AD idea). Klonopin (as do other BZD's) can make sleep somewhat less restful overall despite them being effective at getting you to sleep. Benzos can also aggravate depression in many people. I found that I tend to get worsened depression (I feel "sullen")if I take more than .5mg of Klonopin a day. Diazepam was *very* depressogenic for me in the past. What about... asking your pdoc about switching the Klonopin to a BZD that is shorter-acting and has a better effect on mood such as Ativan or Xanax to take only at bedtime? You should feel less tired the next day and you might sleep better on those two. Ativan really knocks me out. SRI-induced apathy is very real. They can also aggravate insomnia too.


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poster:Ritch thread:124208
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