Posted by Roman on October 20, 2002, at 12:04:48
In reply to SAM-e, posted by Babak on October 20, 2002, at 11:28:48
I tried SAM-e for a awhile and found it somewhat helpful. However, it took some time for it to have an effect on my mood--several weeks I believe. Also, it's important to work up from a small dosage so you can tell how much you really need.
Note the following:
1) Some brands are better than others. I tried GNC, NatureMade and Jarrow. All were fine but the GNC and NatureMade were a little better. The GNC and original NatureMade preparations contained SAM-e 1,4-butanedisulfonate; which is a more stable form compared to SAM-e tosylate (Jarrow and others). Recently, NatureMade switched to the tostylate preparation as well.
2) If it's not fresh, it won't work. Check the exp. date.
3) You must take it on a very empty stomach.
4) You need to take extra B vitamins (folate and B12 especially) or it won't work. I used a B complex and an additional 1000mcg sublingual B12--worked well for me.
5) The bubble-packed products stay fresher longer and the enteric coated products are more effective (wait to disolve in lower GI).
Ultimately, I found it inadequate in relieving my depression--I switched to an SSRI. However, it did have some positive effect with almost no side effects.
Give it some time and see, it might work for you--it does for some folks.
Good luck.
poster:Roman
thread:124356
URL: http://www.dr-bob.org/babble/20021019/msgs/124361.html