Posted by colin wallace on October 12, 2002, at 8:31:11
In reply to SAM-e and SSRI combo....Are they safe??, posted by lawrence s. on October 11, 2002, at 0:15:40
I had great results with sam-e for quite some time, at a very low dose (2/300mg).
I added sertraline at 25mg, and although the initial results were good, I eventually switched to mania- I have since been unable to tolerate sam-e.The sertraline was the most likely culprit in tipping the balance, but essentially it was the combination that did it.
Many people, however, have used the SSRI/Sam-e combo successfully for sustained periods of time.If you have a predisposition for mania/mixed states though, this combo. can really blow your lid.
poster:colin wallace
thread:123175
URL: http://www.dr-bob.org/babble/20021012/msgs/123330.html