Posted by yeltom on October 3, 2002, at 10:49:02
In reply to Re: 30MG LEXAPRO » shakingoscar, posted by pharmrep on October 3, 2002, at 10:35:10
What do you mean 40 celexa and 10 mg of lexapro isn't a 4 to 1 ratio? I'm not comparing the strength of the isomers. I'm comparing the amount of drugs needed to achieve given antidepressant effect. I guess what you're saying is that the s isomer when given alone is twice as potent as the s isomer when given in combination with the r isomer. Seems like a strange point to focus on. People want to know how much lexapro to take if they're on Celexa, and for that purpose, the key a ratio is 4 to 1 (at least roughly).
> > Hi,
> > well I have news for you about this matter.
> >
> > I took JUST 10MG this morning instead of the 30MG which has been making me feel really ill. I feel MUCH BETTER...
> >
> > I dont want to drop from 30 to 15mg in one go, so Im going to move to 20mg as from tomorrow and see how I feel.
> >
> > But I think I am proof that the 2:1 ratio is not true.
> >
> > On a couple of occasions, I took a double dose of my 60mg of citalopram (forgot I had taken it, and took it again if you understand). On the two occasions I have made this error, I was really ill both days. Red face, really trembly, jitters, etc etc..
> >
> > Well, the feeling Ive been getting the last two weeks when taking 30MG lexapro (half my 60mg dose of citalopram) was the same as when I doubled my citalopram dose. I just feel like a fool that I didnt realise earlier that I was on too high a dose of lexapro. I just thought my anxiety had come back!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
> >
> > Well, I will keep you posted on how I get on on 20mg (which if the 4:1 ratio is true), will still be too high and I should move to 15mg... but I want to play it safe.
> >
> > Cheers
> **** 4 to 1 ratio? that is wrong...Lex 10mg vs celexa 40mg is a 2 to 1 ratio not 4 to 1 (dont forget to subtract the r-isomer). anyway...forest is not promoting 4 to 1 either...10mg is 40 yes...but 15=60 and 20=80 is not exact...10mg has been fine for many 60mg+ people (not just celexa...all high doses of AD's). if you already got to 30mg fine, then dropping to 20mg over 2 days or so, then 10 should be fine (not associated w/ discontinuation syndrome) keep us posted.
poster:yeltom
thread:109458
URL: http://www.dr-bob.org/babble/20020930/msgs/122116.html