Posted by Dave001 on September 21, 2002, at 18:46:09
Hi,
Just started tranylcypromine (Parnate) several days ago. It seemed like the logical choice since I have responded best to Dexedrine. Currently I have severe depression, social anxiety disorder, ADD (and probably the rest of the alphabet soup of diagnoses, ad nauseum).
I find it rather frustrating that many people describe various medications as stimulating with an "amphetamine-like effect," when I doubtful whether the majority of these people have actually tried amphetamine. I find that dextroamphetamine in therapeutic doses produces a subjective calming effect, with enhanced mental clarity at the same time. It seems to have a high ratio of CNS/peripheral stimulation. By contrast, many of the so-called "stimulating" antidepressants on the market seem to produce much peripheral stimulation, e.g., agitation and anxiety, but do not enhance mental focus.
I'm going off on tangents here. I have some specific questions.
1.) If you've had success with Parnate for SP, did you feel any initial agitation from the drug? If so, did it dissipate with continued use?
2.) Nardil and weight gain: I know Nardil is infamous for causing weight gain, but what I would like to know, is whether the weight gain is only secondary to excessive eating, or whether it directly influences metabolism or other factors (e.g., insulin sensitivity) which contribute to the weight gain. If anyone has any references to this I would appreciate it if you could post them.
3.) Although I've searched through the archives (both here and Usenet via Google) and have read much concerning this, I would still be interested to hear from people whom have tried both Nardil *and* Parnate (not necessarily at the same time), and which one you found more effective for various symptoms.
4.) Is there any general consensus whether certain dose ranges are more effective for treating one condition over the other? E.g., are lower doses generally more or less effective for SP, while high doses work better for depression? I know these are generalizations and do not apply to everyone, but I'm interested to know if there are any trends concerning this...
5.) Last one: does the initial insomnia go away after awhile?
Thanks, Dave
poster:Dave001
thread:120640
URL: http://www.dr-bob.org/babble/20020914/msgs/120640.html