Posted by Silly Brain on September 19, 2002, at 18:00:38
In reply to Re: Unresponsive to SSRIs? What worked? » oracle, posted by oracle on September 19, 2002, at 15:59:19
> > I'm not sure I understand. Dopamine is affected by stimulants/amphetamines, such as ritalin, dexedrine, adderall...and before they were given to hyper kids for focus they were given to depressed housewives for lack of motivation.
>
> motivation=NE> All amphetimines highly effect NE.
> If dopamine was highly effected
> ones would expect AP like effects.
> Also it does seem that pleaying with dopamine
> can has neast effects.So you're saying that what I've read about amphetamines,
dopamine, and motivation is false. Okay. Sources?Amphetamines in high doses do in fact cause psychosis - this
is what too much cocaine or crank or crystal does. And snorting
lots of ritalin, which people have done. So if you are right
that dopamine is related to psychosis, this still doesn't mean
that amphetamines don't affect dopamine.
> > How do you know you are getting an NE effect as opposed to a 5HT effect?
>
> Prozac at high dose, nothing
> Zoloft, nothing
> Any SSRI, nothing
> TCA's that have a lessor effect on NE are less effective for me.Perhaps my questions was not clear. How do you know it wasn't the
serotonin enhancement from Effexor that helped you? It affects serotonin
differently, and perhaps that mechanism was more helpful than the SSRI
mechanism.What is the difference between a serotonin boost and a NE boost, experientially.
You're claiming that the difference between these is that 5HT boost does nothing,
and NE stops depression. This doesn't explain the people getting help from SSRIs.Silly
poster:Silly Brain
thread:120163
URL: http://www.dr-bob.org/babble/20020914/msgs/120453.html