Posted by turalizz on September 19, 2002, at 8:38:42
In reply to Dr. Bob or other experts: low dose MAOI and diet, posted by Dave001 on September 18, 2002, at 16:31:23
> I have been curious about something for awhile: Isn't it conceivable that one could take low doses of irreversible MAOIs (e.g., for maintenance) w/o having to follow the rigid dietary restrictions?
>
> For instance, if one has inhibited 70% of MAO, I don't see why the remaining 30% wouldn't be plenty to metabolize the potentially dangerous pressor amines. This would of course require careful monitoring and blood work...
>
> My thinking is that perhaps a therapeutic response often requires a near 100% inhibition of MAO. Is this generally the case?
>
> Just to be clear, responses to this post will not be construed by me as any sort of medical advice, etc...
>
> DaveThis is my case: I take 300mg/day moclobemide and 2.5mg/day selegiline. This combination achieves 80% inhibition of MAO-A and some (I don't know how much) MAO-B. I am hypertension free, I can eat everything I want.
Not an expert or anything, but hope this helps.
best of luck,
cem
poster:turalizz
thread:120295
URL: http://www.dr-bob.org/babble/20020914/msgs/120367.html