Posted by Stan on August 6, 2002, at 5:58:21
In reply to Tremendous strides with ondansetron , posted by ryan_s on August 5, 2002, at 21:37:01
> First of all thank all of you for your support over the last four years of my life. These last four years have been extremely difficult. I have been on over twenty different medications without any relief. However, with patience, my hunt for a medication that makes me feel normal and happy has finally arrived. Ondansetron a 5ht antagonist has made a huge difference in my life. The fog has started to lift and this med is allowing me to get back on track with my life. I know that so many of you feel trapped in your current situation. Please Pleas Please, from what I have learned, trust yourself and if a medication does not work, switch medications and do not keep on taking a med b/c your pdoc insists that it will help your in the future. Believe me your will know when a med is making a difference in your life. Also, do not take this the wrong way; I am not fully cured from my anxious situation, but a for the first time in years I feel that I am taking tremendous strides with ondansetron. If any of you have questions please post a reply, and I will get back to you as soon as possible.
>
> Best Regards,
> Ryan
>_______________________________________________
hi ryan -- glad to hear of your success with ondansetron -- i have a few questions if you don't mind.....i've heard of this med before and i know it was formerly used primarily as an anti-nausea agent until researchers discovered that it can also relieve anxiety and depression for some individuals with mood disorders. i've heard that its main mode of action is to antagonize the 5-HT3 group of serotonin receptors, many of which are found in the gut (thus the antimetic effects), but these receptors are also present in the brain. the only other common antidepressant or anti-anxiety agent that blocks 5-HT3 receptors is remeron, as far as i know, and that one has a "kitchen-sink" approach in some respects in that it interferes with all sorts of brain receptors. ondansetron is intriguing from the standpoint of its specificity of action. but i digress.....on to my questions:
how many milligrams of this are you taking per day? are you combining it with any other "mood-drugs"? have you experienced any sedation, dizziness, dry mouth, or any of the other side effects which sometimes go along with antagonism of certain serotonin receptors? what drove you to try this drug -- did you investigate it on your own, or was your doctor "hip" to it already? is it expensive? hope i'm not prying too much, but i'm curious about this one.....
i'd also welcome any comments from other board-visitors who might have some familiarity or experience with ondansetron.
thanks much,
Stan
poster:Stan
thread:115356
URL: http://www.dr-bob.org/babble/20020731/msgs/115381.html