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Re: Colin Wallace - Depakote withdrawal? » Ritch

Posted by colin wallace on August 3, 2002, at 4:53:51

In reply to Re: Colin Wallace - Depakote withdrawal? » colin wallace, posted by Ritch on August 3, 2002, at 0:39:44

Hi Mitch,
>
> Just an FYI, but VPA only has a half-life of 11-17 hrs or so. You might find that taking your Epilim in two divided doses of 200mg each might work better for you-i.e., 200mg at bedtime and 200mg 12 hrs. later.
>
Thanks Mitch,

I did try the 200mg divided dosed for a few days, but it really didn't feel so good at all.I actually woke at 4am with a completely 'dead' leg!No circulation at all,as if someone had tied a torniquet around my groin in my sleep.Never had that before(too active for circulatory probs).Lasted all day too.Wierd.
200mg caps the anger/levels things out, but I'd hoped as they are slow-release, I wouldn't get any probs.Still, as you say, its the half-life that's important.
Strange thing is, despite the startup hiccups(insomnia!! nightmare/wierd dreams/pins 'n needles) I'm feeling much better as a whole.If such a small dose as 200mg can hit the target, then great-otherwise I'll try 400mg divided, as of next week.

Cheers Mitch,

Col.


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