Posted by Shawn. T. on July 25, 2002, at 23:28:43
In reply to Re: DHEA, et al » Shawn. T., posted by BarbaraCat on July 24, 2002, at 0:13:54
Cool ... neuroscience has really grabbed my interest because you never run out of more interesting topics to read about. A lot of other subjects have run into dead ends for me, take philosophy for example. I'm not crazy about all of the animal sacrificing going on either; I'd like to think that we can put the knowledge that we have gained to use in veterinary medicine. I've been sidetracked from fibromyalgia by my realization that receptors can directly interact via G proteins; I have had to reread several things to adjust my thinking patterns. I really wish that someone would have released all the possible interactions between receptors by now; I am having to figure most of these out on my own. Just as an example, I'll list a few possible candidate pairs. Don't look at these as facts, just some possibilities. Certainly don't base any drug decisions on this information. If anyone could point out some that are incorrect, that would be nice. I've got about thirty possible combinations to look up; it's going to take me forever to verify which ones are probable and which aren't.
Guesses:
D1 and 5-HT2a
D5 and 5-HT2c
alpha-1-NA and 5-HT2c
D2 and alpha-2-NA
5-HT1b and 5-HT1d
D1 and D3
D1 and dynorphin
D1 and 5-HT2a
mu and GABAb
5-HT3 and GABAbEven less certain guesses:
alpha2 and 5-HT1a
D2 and glutamate channels
D1 and a dynorphin receptor
D2 and a enkephalin receptor
D4 and 5-HT2b/d
D2 and GABAb
5-HT2a and GABA(a or b)
5-HT3 and NK2
kappa1 and alpha-2-NA
delta and alpha-2-NA
GABAa and D3
5-HT1a and alpha-2-NA
5-HT1a and D2 (presynaptically)
poster:Shawn. T.
thread:1924
URL: http://www.dr-bob.org/babble/20020725/msgs/113749.html