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Re: hypertensive experiences?

Posted by SLS on July 17, 2002, at 15:03:20

In reply to Re: hypertensive experiences? , posted by jsarirose on July 17, 2002, at 1:36:15

Hi.

What are the best drugs to use to treat an MAOI reaction?

I have carried nifedipine (Procardia) around. Is that the best? I had never heard of the usage of Mellaril until someone here mentioned it.

The old recommendation for treating an MAOI hypertensive crisis in the hospital was to use Regitine, an injectable form of phentolamine. Phentolamine is a nonselective NE alpha receptor antagonist that I believe works to relax blood vessels. I'm pretty sure that an oral form was once available, but not since at least 1982. I was hoping that an oral form of phentolamine would once again appear, as it was being looked at for treating erectile dysfunction. However, I don't think the initial clinical studies showed enough efficacy to pursue it as such.


- Scott

 

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