Posted by SLS on June 26, 2002, at 20:48:46
In reply to Re: 3 Beers, did you know...?, posted by Anna P. on June 25, 2002, at 19:17:48
In the past, I have taken:
Parnate 120mg + desipramine 300mg + Dexedrine 20mg + Synthroid
Parnate + Wellbutrin
Parnate + desipramine + Parlodel
I have also combined Nardil with tricyclics
*** VERY IMPORTANT ***
I have not seen anyone successfully combine either Parnate, Nardil, or Marplan with a SSRI or other potent serotonin (5-HT) reuptake inhibitor. I would like to know if anyone else has.
In an act of despiration, I decided once to try adding a small amount of Effexor (venlafaxine) to the Parnate 120mg + desipramine I had been taking. I chose Effexor as a representative of potent 5-HT reuptake inhibitors because it has the shortest half-life - just in case my brain should be offended. It was. I only took 18.75mg. But within fifteen or twenty minutes, I became delerious, babbling nonsense, and unable to stand. It was pretty intense. Fortunately, my parents were in the house. I asked them to take my temperature. It was elevated by about a degree Farenheit, so I wasn't too worried. The reaction subsided within an hour. I got my answer, though. SSRIs, Effexor, and clomipramine are probably best avoided when taking an irreversible MAOI.
Although I would be plenty scared to try it, some Canadian doctors report the successful treatment of TRD patients with a combination of moclobemide (reversible MAOI) with SSRIs. I think Joffe and Bakish are the names most often involved.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8294388&dopt=Abstract
However, there are these:
poster:SLS
thread:107464
URL: http://www.dr-bob.org/babble/20020617/msgs/110876.html