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Re:TCA's » johnj

Posted by Chloe on June 10, 2002, at 21:04:11

In reply to Re:TCA's(Chloe), posted by johnj on June 9, 2002, at 22:03:17

> HI Chloe,
>
> Sorry to hear about the rough night for you. Did you just switched the amit for trimp? Could there be some rebound from changing so abrubtly? My biggest problem right now is how to switch from notry to trimp. I don't think a direct switch will work. My pdoc wanted me to work my way up with imipramine to a theraputic level and then go down, but the problem was I had side effects and some jitterness that spooked me so I dropped the imipramine test. I will discuss trimp in a week.
>
> What I mean by "hosed up" is that when I step up a workout to make it somewhat meaningful I get an overall rotten feeling that starts with sleep problems, depression, enhanced side effects like a return to past dry mouth and especially dizziness. Doc says it is not the med, but I have found people that had the same problem on amitryptline which is the parent drug of nortry; however, they didn't have the problem on imipramine. So, the TCA's are not all equal like the ssri's are not equal. Excercise is my way to help myself which is very depressing when I cannot. This odd effect after working out usually came about after a certain period of time, but recently, probably due to being in my 30's, it has started to happen more quickly. I take lithium and some benzo, but have not heard from anyone that these have caused this feeling. Last fall I was into my 4th week of jogging again and started to feel like crap. It took over 2 weeks to work itself out. I had started a new job 6 weeks earlier so I thought that might also be a reason for some troubles again. So, I waited a month or so and tried lifting and after a few weeks felt like crap again. Sorry to ramble, but that is the readers digest version my TCA experience.
>
> I am interested in trimp for the sleep aspect. I might have to give up excercise until something better comes along. I am not very interested in ssri's since they may cause some panic attacks and I want to avoid anything that may cause anxiety and panic with depression. Again, check with your doc about switching the meds slowly. I am not sure the best way, but cold turkey might have some withdraw effects that have nothing to do with the trimp. Hope all goes well and you get some sleep. Hang in there we are all in this together.
> Peace
> Johnj

Well,
I am sorry you are having difficulty with TCA's and exercise. What you describe is really the pits. And it must be hard that you pdoc doesn't think it's the med. I think problems like you outlined should be taken seriously. And exercise is so essential to feeling well and being healthy and fit.

Are you drinking enough water? I know that sound silly, but with the Li and Nort. I think you must get dry as a bone when you sweat. You must have to drink at least an extra gallon when you are working out. I know I need soooo much water, esp. since I added amitrip 20 mgs. It's amazing how much water I can drink, and I don't pee that much. FWIW. You might try flooding yourself before, during and after workouts, see if it makes a difference?

I don't recommend swapping one med for another, unless they are truly "sister" drugs. Make sure you have a plan established with your pdoc if you do plan to transition to trimip. Because for me, dropping out Amitrip 20 mgs, and taking trimip 25 mgs in it's place really messed me up. I had chills and sweats, heart palps, and insomnia, restlessness, stomach problems. And I also think I have some exacerbation of my TD in my mouth. (Trimip does touch on dopamine, so if you have any TD issues, this is a TCA I would avoid.) But who knows what was withdrawal and what is just the side effects of a new TCA? All the things I mentioned are listed in the adverse reactions of all the TCA's, trimip and ami included. I am waiting to hear from my pdoc about what I should "do" about trimip. I d/c'd it last night. I was so scared to take it again and NOT sleep and feel so agitated, and possible have my tongue movements increase. Taking the smallest amount of ami 10 mgs settled me, and I slept so well :)

Well, I think I am rambling. My body is still reeling from this. Feel kinda yucky. Keep me/us posted on what happens next for you! Do you think your pdoc will go for a trial of Trimi? Is he a fan of this drug? My pdoc seems to be, I wish I know why....

Chloe


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