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Re: dopamine to noradrenaline » turalizz

Posted by Ritch on June 6, 2002, at 10:15:37

In reply to dopamine to noradrenaline, posted by turalizz on June 6, 2002, at 5:21:21

> Hi,
>
> Selegiline, in the MAO-B selective dose range would increase the dopamine levels, and since dopamine is the precursor to noradrenaline, selegiline would also effect noradrenergic transmission indirectly. Am I wrong?
>
> cem


Yes, it would. Perhaps a more important player is one of selegiline's metabolites-methamphetamine. That one definitely releases noradrenaline and blocks its reuptake.

Mitch


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poster:Ritch thread:108919
URL: http://www.dr-bob.org/babble/20020602/msgs/108941.html