Re: Memantine / Amantadine

Posted by JohnX2 on June 1, 2002, at 20:23:52

In reply to Memantine / Amantadine, posted by Seamus2 on June 1, 2002, at 9:28:01

> Hi Scott,
>
> Have you done a Medline on amantadine for the same use? I think they are chemical cousins and iirc, amantadine is a DA agonist.
>
> Seamus
The two medicines are are almost molecularly identical.
Memantine has 2 extra CH3 groups.
I don't know how the physiological properties compare.
Are they apples-to-apples?
The molecular weight of memantine is greater than
amantadine. But the therapeutic dose for memantine
off the top of my head is around around 30mg and
amantadine is 200-400 mg. Supposedly amantadine is
much more intolerable.
John

Thread

Keppra for hard-to-treat Bipolar Disorder Psydoc 5/25/02
...
thankyou (nm) katekite 5/27/02
fyi susan C 5/27/02
Re: fyi Psydoc 5/27/02
Re: Dr Goldberg, so there is no hope? Anna P. 5/29/02
Re: Dr Goldberg, so there is no hope? » Anna P. Psydoc 5/30/02
Re: Keppra for hard-to-treat Bipolar Disorder » Psydoc JohnX2 5/30/02
Re: Thank you! Anna P. 5/31/02
Re: Keppra for hard-to-treat Bipolar Disorder » JohnX2 Psydoc 5/31/02
Re: Dr Goldberg, so there is no hope? Anna P polarbear206 5/31/02
Re: Dr Goldberg, so there is no hope? » Psydoc SLS 5/31/02
Memantine / Amantadine Seamus2 6/1/02
Re: Memantine / Amantadine - Thanks :-) (nm) » Seamus2 SLS 6/1/02
Re: Memantine / Amantadine JohnX2 6/1/02
Hope Cecilia 6/2/02
Re: Hope » Cecilia JonW 6/2/02
Re: Hope Anna P. 6/2/02
Re: Hope and complex drug cocktails » Cecilia Psydoc 6/2/02
Shouldn't he be taken off the Antidepressants? » Psydoc JennyJen 6/2/02
Re: Hope » Anna P. Cecilia 6/3/02
Re: Hope and complex drug cocktails » Psydoc JonW 6/3/02
Re: Hope and complex drug cocktails » JonW Psydoc 10/4/02

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