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New Mood Stablizers Unproven

Posted by JohnnyS on May 26, 2002, at 23:24:14

Hey Everyone,

Could someone help me with this. So far, this is the status of the new anticonvulsants in psychiatry. Anyone with more informative, please add to it. Thank You.

1. Neurontin: Studies shows placebo better than neurontin for bipolar disorder, company has abandoned FDA approval.

2. Lamictal: One study with mild to moderate efficacy in bipolar depression. I think in phase III study.

3. Topomax: I read on "Psycheducation" web site by Dr Phelps that preliminary studies were poor and that the company is stopping seeking approval by the FDA.

Many doctors still use these meds as first line over lithium and depakote when studies are negative. Does anyone know why this is. Thanks.

JohnnyS


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poster:JohnnyS thread:107689
URL: http://www.dr-bob.org/babble/20020525/msgs/107689.html