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re: Provigil pooped out 2 months/ old guard ADs

Posted by 3 Beer Effect on May 13, 2002, at 21:29:52

In reply to Re: No resp.=Depress-severe/Need help w/ old ADs! » 3 Beer Effect, posted by IsoM on May 13, 2002, at 14:53:37

IsoM,
The Provigil worked good for getting me out of bed in the morning at 200 mg/day. It didn't work that well for ADD/concentration, nowhere near as well as Ritalin & didn't help that much socially as it does some- It felt to me, exactly like extended release No-Doz (caffeine).

At first it lasted a very long time (all day), but eventually it started losing efficacy after a little over 2 months & soon after that it only worked for 4 hours, then zero.

So I switched to Dextrostat & am doing much better on that. Currently take 20 mg 2x per day. Dexedrine/Dextrostat is a wonderful anti-depressant, social disinhibitor, ADD medication but unfortunately it only lasts 4-5 hours. So during the 6 hours per day that i'm awake & its not working I feel severly depressed. In other words, the Dextrostat isn't enough of an anti-depressant on its own.

None of the new ADs have worked for me (Celexa, Effexor, Remeron, Lamictal, Neurontin) except Zoloft 100 mg which worked wonderfully for both depression & social phobia but made me an insomniac & I think because of the sleep deprivation eventually manic- but the psychiatrist could have fixed that with a benzo or ambien or Remeron for sleep &/or by lowering the dose to 75 mg, but he didn't, suffice to say he is no longer my psychiatrist.

I can't take Wellbutrin SR because I had a Soma muscle relaxer overdose a few years ago & had three small siezures- I don't think your supposed to take Wellbutrin if you've ever had a seizure.

I've read sometimes AD non-responders/severe depressives have to turn to the "old guard" antidepressants like tricyclics or MAOIs to get relief. It seems like the MAOIs especially have a very high cure rate compared to SSRIs.

So I'm thinking of asking the psychiatrist for Desipramine or Vivactil (protriptyline) or the MAOI Parnate. All three of these are supposed to be stimulating, & I seem to respond to stimulating ADs best (Remeron was a nightmare for me). The side effects of these old drugs though, sound pretty severe & I don't know much about them.

Thanks,
3 Beers.........


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poster:3 Beer Effect thread:106073
URL: http://www.dr-bob.org/babble/20020510/msgs/106251.html