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Re: What about Klonopin, Depakote and GABA... » Janelle

Posted by JohnX2 on May 8, 2002, at 1:00:17

In reply to What about Klonopin, Depakote and GABA..., posted by Janelle on May 6, 2002, at 4:46:05

> I have read that Klonopin and Depakote both work on GABA, but apparently in different ways. I don't understand how each of these meds works on GABA and would very much appreciate it if anyone who knows how they each affect GABA could explain it briefly and as simply as possible. Thank you!

Here's a paper I dug up on Gaba:

http://www.vcu-cme.org/gaba/gaba2_22.pdf

One should note that there are various types of
Gaba receptors; namely Gaba-A and Gaba-B.

Klonopin and most benzos work at the Gaba-A receptors.

Depakote from what I understand has some affinity for the
Gaba-B receptor.

John


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URL: http://www.dr-bob.org/babble/20020503/msgs/105535.html