Posted by Janelle on May 6, 2002, at 21:33:02
In reply to Re: What about Klonopin, Depakote and GABA... » Janelle, posted by Ritch on May 6, 2002, at 13:31:00
Thanks for explaining what you know about the differences between Klonopin's and Depakote's effect on GABA ... I have just one follow-up question if you don't mind:
You said that Klonopin acts at the GABA receptors (like other benzos) - what does this mean - what does it *do* at the GABA receptors? Does it do what SSRI's do at their respective receptors, meaning some kind of blockade of GABA reuptake so there would be more GABA flowing in the brain?
I ask because I've been on Klonopin a long time and then had that HORRIBLE reaction/deep depression when I began with Depakote, so I'm wondering if maybe I got a GABA overload since you said that Depakote tends to promote GABA synthesis (your brain makes more of it) and I'm wondering if Klonopin also does something to have more GABA floating in the brain?
Thanks!
poster:Janelle
thread:105245
URL: http://www.dr-bob.org/babble/20020503/msgs/105350.html