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Re: Most treatment resistant person, ever... » tb

Posted by BarbaraCat on April 22, 2002, at 12:56:20

In reply to Most treatment resistant person, ever..., posted by tb on April 19, 2002, at 15:03:55

Hi Treatment Resistant One,
And I thought I had that dubious honor! I've been on every last one of the SSRIs and their spin-offs as well as the older TCAs over the past 20 years. They'd work for a while then depression would eventually break through and any dosage increase resulted in anxiety, insomnia and grinding of teeth. What's finally worked is recently adding Lithium and Klonopin to my Remeron. The Lithium supercharges the Remeron yet leaves me feeling even-keeled. I suspect the lithium would work with any of the ADs to prevent poop-out, but I like Remeron because it works best with my depression/anxiety profile.

I tried Topomax to hopefully replace the Lithium (weight gain), but it made me feel horrible. The weight gain is an issue, but the only magic bullet to deal with that is getting to a place where I can whup my body into some daily exercise. Moving that stuck energy has also proven to be absolutely the best antidepressant for me, but totally impossible when I'm feeling really bad. Good luck and don't give up. The mood stabilisers seem to be the missing ingredient in the AD mix for many of us here. It's just patiently wading through til you find the right one. - Barbara

> Hey everyone,
> I am really discouraged. I must be THE most treatment resistant person EVER. I have been suffering from bulimia for the last 12 years. I have been on EVERY AD out there - prozac, zoloft, wellbutrin, effexor, buspar, serzone, remeron, clomipromine, naltrexone. I've also tried topamax, adderall, ritalin, and dexedrine to help potentiate the drugs. NOTHING HELPS. I don't even get the bad side effects from drugs anymore.
> I tried Topamax last week, full dose, and it didn't even make me tired let alone help with the binge eating.
> Does anybody out there have any ideas of what route I should take. My pdoc is stumped...guess it's time to find a new one?
> Thanks
> Tb


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