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Re: Zyprexa question

Posted by xjs7 on April 17, 2002, at 23:57:39

In reply to Zyprexa question, posted by Margit on April 17, 2002, at 22:47:06

Hi Margit,

Olanzapine [Zyprexa] has anticholinergic effects according to the prescribing information: "Olanzapine's antagonism of muscarinic M1-5 receptors may explain its anticholinergic effects." Another document I checked lists olanzapine's receptor blockade of M1 as high.

Due to your acid reflux problem, another drug might be better. Risperidone [Risperdal] and ziprasidone [Geodon] have no appreciable affinity for the cholinergic muscarinic receptor.

xjs7


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