Posted by Ritch on March 31, 2002, at 16:29:06
In reply to Re: zyprexa for atypical depression? » OldSchool, posted by SLS on March 31, 2002, at 14:51:40
> The following drugs made me think about suicide more:
>
> amoxapine (Ascendin)
> bupropion (Wellbutrin)
> idazoxan
> mirtazepine (Remeron)
> moclobemide (Aurorix, Manerix)
> protriptyline (Vivactil)
> reboxetine (Edronax)
> triiodothyronine (Cytomel)
>
> I hope no one decides not to try one of these drugs based upon my negative experiences with them.
Hi Scott,Your list of meds that aggravate suicidal ideation is somewhat interesting to me. I noticed they are all principally noradrenergic meds (for the most part). The only time I have any remarkable suicidal ideation is whenever I am in a mixed dysphoric state (hostile and/or anxious/agitated depression). I realize that SSRI's have had a rap for causing that, but I found in my own experience if they chill out my anxiety and I can remain reasonably focused, the ideation is reduced a lot. I had to break down today and try a little chunk of Celexa (2mg), and yeah sure enough here comes that wave of alerting numbness sweeping over me, but everything is just okeedokee now. Add 2.5mg of dexedrine and I feel fine. The dex. is actually making me a little drowsy feeling. My head seems a little hot right above my eyebrows, but I feel ok. It seems that the *trick* for me is to directly boost serotonin and dopamine, but try to avoid "hitting" the NE receptors (at least directly anyways). The worst meds for agitation or dysphoria seems to be stuff like Remeron/Effexor/Wellbutrin, primarily noradrenergic meds like those in your list. I wouldn't worry too much about scaring people away from decent meds, there is enough bad rap to scare them anyhow. Besides you will hear success stories with stuff like Effexor, Remeron from others here anyway. I am just curious why people (even with the same dx) can have such different responses.
Mitch
poster:Ritch
thread:100817
URL: http://www.dr-bob.org/babble/20020327/msgs/101147.html