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GHB pharmocolgoy

Posted by geno on March 28, 2002, at 19:45:07

GHB pharmocology is a very misunderstood phenominon. Most people thing ghb is just a sleep aid, or used for date rapes. THOUGH ghb has numerious theroputic uses.
First ghb is a neuroleptic/gaba enhancer all in one. Is blocks dopamine release and binds gaba b receptors. Also ghb releases oxytoxin, which is theory is related to social activity. GHB at higher doses is used for deep rem sleep. A sleep that one cannot be awakened for 2-4 hrs. GHB is the fastest mood enhancing, antianxiety agent known. Also it can be used for schizofrenia symptoms, but not avised due to quick metabloism and dopamine rebound effect.
GHB has well been known though media as the date rape drug.Well im my opinon, it would be a poor date rape drug. Why? because say a "date rapist' slips ghb into an unsuspecting females drink. She passes out. he begins to rape her. BUT, at anytime, this female can be awakened from the ghb effect. I would speculate roofies, valium at high doses, or even ambien would be far more effective in a date rape situation.
GHB is a metabloite in the body, vitually non toxic to bodily organs. Its a simple carbohydrate and is eliminated via hydrolosys, more so susnicic acid, in the krebs energy cycle.

GHB was studied on suicidal subjects. A moderate dose of ghb given to a suicidal subject could quickly alter ones mind into not committing such act.

GHB is illegal. THis is the main purpose not to use or posses such. Though fda appoval this year will make it a schedule 3 drug for the treatment of nacolepcy. GHB puts on into deep rem sleep, which persons with narc cannot produce.

I have many more subjective findings on ghb.

geno


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