Psycho-Babble Medication | about biological treatments | Framed
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Re: Usually not

Posted by OldSchool on March 22, 2002, at 16:13:34

In reply to Will tricyclic sedation wear off?, posted by Lia Mason on March 22, 2002, at 12:39:40

> I'm trying to build up to a therapeutic imipramine dose but at 60 I'm already tired. As I need to go to 200, this is discouraging. My doc says if I soldier through--over months--it will eventually subside. Anyone have experience that speaks to this? I already failed on nortriptyline which made me totally lightheaded and woozy.
>
> Thanks!
> Lia


Lia, usually TCAs are quite sedating. Tofranil is one of the most sedating antidepressants there is. Its from the anti-cholinergic side effects, thats a big part of it. I took Pamelor once for a few months and the sedation never went away. TCAs are just generally very sedating drugs, with the one exception of desipramine which some people like and claim is somewhat stimulating.

If it were me, Id be opting for a modern class antidepressant. The modern class ADs generally have a much more tolerable side effect profile.

Old School


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