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SLS: re Serotonin syndrome, more: » SLS

Posted by Janelle on March 15, 2002, at 17:13:40

In reply to Re: My intuition says no to Effexor + Luvox. . . » Janelle, posted by SLS on March 15, 2002, at 10:47:58

Hi,

First, the reason that you had such a bad reaction when you took a very small dose of Effexor - less than 20mg - while you were taking Parnate (an MAOI) is because there are warnings all over the place NOT to mix SSRI's with MAOI's. I imagine the dilirious stupor you wound up in where you were confused and babbling nonsense was because apparently SSRI's and MAOI's do not mix! I have read all over the place not to take them together and also if you're going to switch from one to the other you should wait 14 days before making the change.

As for the sorts of things I experienced that brought me to the conclusion that I had gotten serotonin-syndrome from the high dose of Luvox plus a moderate dose of EffexorXR well it's a blur now (my memory is shot thanks to the depression condition and I think the meds too), but I recall that I had the shakes and tremors big time, headaches, my head also *jiggled* inside. It was mostly the shakiness and feeling over stimulated, an overly caffeinated type feeling. I almost felt like I was on a high. It was my sister who first thought it could be too much serotonin and then when I had a visit with the pdoc she immediately said it was probably SS after I described my symptoms. That was what made her decide to titrate me down on the Luvox and lo and behold the symptoms went away. That this happened also led us to conclude it had to be SS.

I'm encouraged to that you mentioned that Effexor does not seem to "poop-out" nearly as often the SSRIs do because I am still very bummed out that Paxil which had worked wonders for me suddenly pooped out and I've not been able to stabilize since then yet.

take care
-Janelle


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