Posted by Thrud on March 12, 2002, at 4:47:45
In reply to Re: Hypopthyroidism in people wioth mood disorders. » Thrud, posted by JohnX2 on March 9, 2002, at 1:14:44
Hi John,
> I've looked into and also tried l-tyrosine and
> also l-phenylalanine suplemenatation with short lived poop out
> results.I get the feeling that the body has "thermostat" levels set for just about every chemical in the body, and if it is a natural substance like tyrosine, it quickly figures out how to counter-act elevated levels (extra liver metabolism etc?).
It seems to take a fair time longer to figure out how to counteract (unnatural-to-the-body) psychmeds but does seem to eventually succeed in most people.>My understanding of the biological pathway is that the
> amino acid in the vast majority of neurons already saturates
> the bottlneck enzyme called "tyrosine hydroxylase".
>
> phenylalanine (via phenylalanine hydroxylase)-> tyrosine (via tyrosine hyrdroxylase)-> l-dopa -> dopamine -> norepineprine
>Yeah, I had a look at the metabolic pathways one day as well and noticed a possible bottleneck in tyrosine hydroxylase. I then bought some NADH which supposedly helps depression by increasing the production of tyrosine hydroxylase. It didn't really do much for the depression and also made me somewhat impotent. I don't really recommend it to anybody.
>So I wonder if your effect had
> more to do with norepinephrine than dopamine.
>
> -JohnI can't say. L-tyrosine is also used in the thyroid, thalamus, hypothalamus and adrenal glands. Any one of these could be screwy too. My low testosterone and LH levels has now given me an excuse to see an endocrinologist, so I will ask for a full work up.
I can't stand enforced celibacy for much longer................
Thrud
poster:Thrud
thread:96147
URL: http://www.dr-bob.org/babble/20020307/msgs/97569.html