Posted by Ritch on March 6, 2002, at 0:30:27
In reply to Re: Zonisamide- one more question, posted by Geezer on March 5, 2002, at 14:07:45
> > > Mitch, John, and others may recall my adventure from the recent past. I am Bipolar II, was stable on 1000mg. Dep. and Remeron 15mg. (refractory TRD persists with this combo). The old pdoc (now fired) pushed the Remeron to 30mg. resulting in dysphoric hypomania (mixed-state ?). Options coming up next Tues. 11th:
> > > 1) Increase Dep. to 1250mg and increase Remeron to 30mg.
> > > 2) Increase Dep. to 1250, leave Remeron at 15mg. and add Modafinil slowly.
> > > 3) Leave Dep. at 1000mg, leave Remeron at 15mg., and add Zonisamide as part of a research study next month.
> > >
> > > This is all being done under the supervision of 2 pdocs, one a treating pdoc, the other in research and in control the Zonisamide part of the plan.
> > >
> > > Geezer
> >
> >
> > Geezer,
> >
> > What sort of thing have these pdocs told you about Zonegran, if anything? What sort of things are they trying to solve by adding it on-if you don't mind me asking? I am just trying to figure what the skinny is in their heads by offering the trial.
> >
> > thanks in advance,
> >
> > Mitch
>
> Hi Mitch,
>
> Don't mind your asking at all......infact at this point I am beginning to ask the same question. The purpose, as stated, is to determine the effects the drug will have on mania and depression. Please forgive me for not giving names and places Mitch...I just can't publicly convey that information. I have been recording in a mood chart since November 1, 2001 -drugs taken daily, moods, changes, depressed, manic, dysphoric, etc.
> I have been guilty of not holding drugs used at a constant level and the treating pdocs introduce new drugs that confuse the issue. I am disquaified from trial add on drugs (for the purpose of the study) for these reasons. To put it in simple terms "the left hand doesn't know what the right is doing". The last CHARGE leveled at me was "you have trouble trusting people". After 30 years of this I think its about time one of them "earned" some trust. The research pdocs have the answers but won't discuss the issues......the local pdocs should have been shoemakers.
>
> Geezer
I can understand them being secretive-not wanting to "spoil" the objectivity of the study by letting you in on too much. I am really NOT interested in their names or any of "their" research really. I just wondered what *they* told *you* about *why* they were wanting *you* to engage in the trial. I just wondered if they allowed *you* to pick *their* brains or not. Obviously not.I would bring up the objectivity question to them and then see what they (all) say.....
You could bug them about a conference between all of you to address *all* of these issues. Why not??hope you can fine some humour in this :-)
Mitch
poster:Ritch
thread:96489
URL: http://www.dr-bob.org/babble/20020301/msgs/96637.html