Posted by Jason911 on March 4, 2002, at 12:14:43
In reply to Re: Wellbutrin increases or decreases dopamine? » Jason911, posted by Ritch on March 4, 2002, at 10:30:46
The reason why your doc won't prescribe MAOI's like Nardil is because you are bipolar and could induce a manic state. Have you given lithium a try? -Jason911
> Jason,
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> Thanks for the reply. I have brought up selegiline to my pdoc before and MAOI's of *any* kind will not be prescribed, period. In my case I was trying to find something for my ADHD probs that wouldn't make me as anxious as Wellbutrin or pstims (and also not as likely to aggravate bipolar mood cycling as much as TCA's). I *have* to have a script for selegiline here to take it however because of the potential for random urine tests at work. When it metabolizes there is going to be some unchanged methamphetamine excreted by my kidneys that a test will pick up. If I drop a box on my toe at work I am going to be SOL. Maybe my pdoc would reconsider the transdermal version?
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> Mitch
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> > I don't see Wellbutrin as anything but an "upper" similar to coffee in the morning. And the effects like insomnia are not uncommon. Probably due to the high levels of NE keeping you uneasy and unable to sleep. Like germanium said, if you suffer from depression (since you respond to the stimulation effect meds) try low-dose selegiline (5-10mg) and supplement with around 600mg/phenylalanine (presurser to PEA) daily. Phenylalaine is cheap. GNC sells 30 100mg tabs for $10. Selegiline via mail-order is cheap (Jumex - same as US Eldepryl but ALOT cheaper) $47 with s&h inc. gives you 50 5mg tabs! 50 Days worth! And as for sleeping and being more eased and more social I'd augment 2-3mg Klonopin a day. You'll have no problem getting to sleep. I'd guess you'd do well with the Klonopin at 1mg in the morning, 1mg at noon, and 2mg - 2 hours before bedtime. Hope this helps -Jason911
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> > > Hi John,
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> > > Very good stuff indeed. I am still on WB with other meds and my personal experience with taking the med seem to correlate with your talk about the active metabolites, etc. I like the "straight" bupropion right after a dose in the morning with some strong coffee. What I do *not* like is all the pharmacological "baggage" that hangs around late in the day culminating in irritability or in difficulty sleeping. That highlights something I really miss about taking Adderall. It gets to "work" quickly and leaves your body when it is time to sleep. A lot of people are out there taking a lot of "unintended" medications that are active metabolites with very different modes of action than what is "showcased".
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> > > Mitch
poster:Jason911
thread:96141
URL: http://www.dr-bob.org/babble/20020301/msgs/96327.html