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Re: duloxetine approval » SLS

Posted by medlib on March 2, 2002, at 3:27:32

In reply to When is duloxetine to be approved?, posted by SLS on March 1, 2002, at 9:48:21

Hi Scott--

It's great to see you posting again! As you know, I really can identify with not having enough energy or concentration to post; so, no intent to lay a guilt trip, you're just missed. Sorry things have been so rough for you of late--fill us in when you can.

I wouldn't hold my breath waiting for duloxetine. Final approval is being held up by FDA concerns over Lilly's manufacturing quality control. The company failed its most recent reinspection, but it's still projecting final approval in the second half of 2002. Others say "late second half 2002". Reportedly, duloxetine's advantage over Effexor is that it doesn't raise BP. I haven't seen any reports of clinical efficacy for depression superior to Effexor (but I haven't done a thorough search).

Naturally, I could blather on indefinitely, but I've agreed to care for new grandson (my first) in a few hours (8a-6:30p), so I'd better at least *try* for a little sleep. My current rx combo (Effexor, methylphenidate, and Wellbutrin) probably could keep the dead awake--guess I'm about to find out.

More later, if I live that long---medlib


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