Posted by Gray on March 1, 2002, at 12:57:32
In reply to Re: Feeling spacy/Anyone at 300 mg with Effexor?, posted by rxcuriousity on January 23, 2002, at 4:19:58
> So glad to see your post, Sarah. I've been on 225mg of Effexor XR for about 6 weeks. I started at 37.5mg and slowly titrated up over two months. I had that "UP" feeling that you described up until about a month ago. I loved that feeling, and am trying to get it back. I felt so on top of my game. I had energy, felt social, was very motivated, and was not anxious at all. Typically drugs that make me feel that "UP" make me quite anxious.
>
> I haven't experienced any recurrence of symptoms [of depression or anxiety] but have been very tired and kinda unmotivated. I am working with my pdoc on finding an effective adjuvant . . . something that will bring me back to that "UP" state. I'm not necessarily looking for excessive stimulation, or appetite supression, but I would love the sociability, confidence, and motivation to return.
>
> I recently added 100mg of Wellbutrin to try to get that feeling back. If the Wellbutrin trial is not successful, I will probably next try kicking the Effexor up to 300mg. Another strategy might be to add a stimulant. I have to be careful, though. I suffer from both depression and anxiety.
>
> Let's continue to share our stories and hopefully return to that state that we both enjoyed so much.Hi,
I know exactly what you mean about that initial "up" feeling you experienced with Effexor. I've had that same experience with imipramine. It is my beleif that the "up" feeling comes from dopomine centers getting excited and over time they calm down. I have found that the "up" feeling can be brought back with small amounts of dexedrine. Keep in mind that dexedrine goes into your system and out again quickly.
Therefore sometimes it is appropriate to use the slow release spansules (15mg) in combination with the 10mg tablets. I find for myself that I have to continue taking the dexedrine for 48 hours along with my regular medication. After 48 hours I find I can taper back on the dex. I'm bi-polar and
have to be careful not to fly too high. So once I have "jump-started" my AD medication again, sometimes I have to take zyprexa (5mg/day) to calm things down. For me personally, it is a balancing act. The whole process has
required a lot of trial and error over years. I can say this. Never give up! The periods of "up" are a sure
sign that a better life is available and that there is escape from mental anguish.
Be Well,
Gray
poster:Gray
thread:91210
URL: http://www.dr-bob.org/babble/20020301/msgs/95963.html