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Re: Metabolism of Wellbrutin » mdertinger

Posted by Sunnely on February 28, 2002, at 19:48:56

In reply to Metabolism of Wellbrutin, posted by mdertinger on February 28, 2002, at 8:15:31

Bupropion (Wellbutrin) is metabolized by the liver. The be more specific, the parent compound (bupropion) is metabolized by CYP2B6 and CYP3A4 while the metabolite, hydroxybupropion, is metabolized by CYP2D6.


> An earlier post mentioned that Wellbutrin is not metabolized by the liver..... Is this true?
> I thought all SSRI's were metabolized by the liver.


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