Posted by JohnX2 on February 28, 2002, at 1:47:12
In reply to PsychoStimulants and Depression, posted by George on February 27, 2002, at 5:03:39
Wow, sorry for the AD horror story.
I don't disagree with stims as a last ditch
depression treatment effort.Have you tried mood stabilizers?
Here are a couple of thoughts:
1) Lamictal - Great Reputation for treatment resistant depression
2) This is a way out there suggestion:
Acamprosate (an alcohol addiction medicine)
+ memantine (a neuroprotective medication)
Both of these medicines have been shown to
reduce tolerance/sensitization to opiods/ethanol/stimulants. This may turn your system back "on". Also may allow ADs to work.
Totally investigational thought. A few people on
this newsgroup have reported success using memantine (Akatinol) to alleviate tolerance to Adderall. The medicines are in clinical trials in
the US, but are available in Europe with a prescription.Sorry to hear about your plight.
Regards,
John> Hello. My physician decided to put me on stimulants after three years of unsuccessful treatment with 26 different antidepressants and combinations. Treatment with Adderall worked almost immediately and miraculously--giving me my life back for thirteen months. About a month ago, the Adderall started giving out, and now I'm back to a consistently depressed state. My depression is not any worse than it was before the stimulants--the same old thing. I don't drink very much--two or three drinks once per week. I've had partial success with the combination of Provigil and Wellbutrin. I'm also considering giving Dexedrine a try. Any advice?
>
>
> > For your depression, was your precribing physician
> > specifically choosing to use psychostimulants to treat
> > your disoder? Over time this may interfere with your bodies
> > natural reward mecanisms. As well does drinking. So for getting
> > depression treated, typically one will go on anti depressants
> > and cut down on stims and alcohol in order to reorganize the
> > brains reward system. I find its ok to have a drink every now
> > and then , but excessive drinking depletes the brain of important
> > chemicals and intereferes with the depression treatment process.
> >
> > Good luck with your treatment.
> >
> > -John
> >
> >
> >
> >
> >
> >
> > > I have recently fallen into a deep depression that I had under control for 13 months through stimulants. I notice that in my depressed state, it takes much longer for me to get drunk--my tolerance is noticeably greater than when I wasn't depressed. Does this mean anything or does it hold any clues as to what chemicals are lacking in my brain? Thanks.
poster:JohnX2
thread:95598
URL: http://www.dr-bob.org/babble/20020222/msgs/95782.html