Posted by Else on February 26, 2002, at 22:15:46
If MAOIs were viewed as more effective than TCAs for the treatment of atypical depression and social phobia before the arrival of Prozac, then why are we comparing new antidepressants to imipramine or, simply placebo. SSRIs may be as effective as TCAs as far as these disorders are concerned but so what? If TCAs are not that effective to begin with, this is completely irrelevant. Is anyone aware of one single study comparing a standard MAOI like Nardil or Parnate with Prozac, Paxil, Zoloft, Remeron, Effexor or any other new drug for that matter, in the treatment of SP and/or Atypical depression? I looked everywhere but I couldn't find anything. Are we putting up with less effective drugs because they don't make GPs (and some pdocs) as nervous? My doctor continues to refuse to give an MAOI a try even though, based on my symptoms, these drugs would probably be the most effective ones. I think I have a right to know. Am I putting up with this "so-so feeling" because there is no alternative or because the alternative is something my doctor is uncomfortable with? I would be very grateful if anyone could provide some information about this.
poster:Else
thread:95651
URL: http://www.dr-bob.org/babble/20020222/msgs/95651.html