Posted by spike4848 on February 14, 2002, at 18:27:26
In reply to Re: Wellbutrin vs. SSRI, posted by BLPBart on February 14, 2002, at 0:01:29
> There are three neurotransmitters in our brains that these ADs work on. The SSRIs only work on serotonin. Wellbutrin works on norepinephrine and dopamine so it works very differently.
My vote is none of the above. With over 200 neurotransmiters in the brain, how do we know the antidepressants work on serotonin, dopamine and norepinephrine. And just because the drugs affect these neurotransmiters in a test tube in a rat neuron, why should we assume they do the same in a human being. Antidepressants probably work somewhere further downstream, at the level of the nucleus affecting mRNA coding or the second messanger system.
Spike
poster:spike4848
thread:93156
URL: http://www.dr-bob.org/babble/20020208/msgs/94156.html