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Lamictal as anti-depressant- how? what doses?

Posted by 3 Beer Effect on February 8, 2002, at 17:43:08

I am starting with 25 mg of lamictal/day as a mood-stablizer/antidepressant & my dose is to be increased by 25 mg each week. I am quite depressed & was wondering at what dose range does Lamictal work as an anti-depressant. Is Lamictal as strong of an antidepressant as the SSRIs (which I can't tolerate-mania/insomnia). I take the lamictal once at night because it seems to cause nausea for me- Why do some people take it twice a day if the half life is 32.8 hours?

Why does Lamictal have anti-depressant properties? It only has a "weak inhibitory effect on the serotonin 5HT3 receptor & weak effects at sigma opoid receptors." "Lamictal did not inhibit the uptake of serotonin, norepinephrine, dopamine, or aspartic acid."


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poster:3 Beer Effect thread:93340
URL: http://www.dr-bob.org/babble/20020208/msgs/93340.html