Posted by Rick on February 8, 2002, at 5:07:34
In reply to SP how do we conquer it??????? Nardil, posted by ross on February 1, 2002, at 21:40:42
Nardil can be fantastic for lots of people with Social Phobia. It's the gold standard among AD's for SP, even if it gets shunted aside for a couple of valid concerns mixed with tons of exaggerated MAOI paranoia.
As Spike mentions, Klonopin+ Serzone + 100 mg Provigil has been a "wonder cocktail" for my non-depressive SP for well over a year now. Klonopin + Provigil, without the Serzone, is a bit less robust but still a damn powerful treatment for me.
When I first started Klonopin, after trying many other meds including Celexa, Xanax, Neurontin,and lots more, it was a godsend. The combo with Provigil and Serzone takes it to an even higher level, adding welcome new dimensions such as confidence, enthusiam, and proactive sociability to Klonopin's powerful social-fear-allaying powers.
Nothing has ever tested higher than Klonopin in placebo-controlled SP studies, not even Nardil.
See abstract below. But don't take this as a suggestion that you move away from Nardil, because again it works so well for so many social phobics -- certainly far better than heavily-marketed Paxil. And, in case weight gain is a concern for you, I should point out that I started my first-ever earnest diet while taking Nardil, and the pounds came off more easily than I ever expected. (I sometimes wonder if this was helped by the fact that, at the time, I was ignorant of Nardil's reputation for weight gain.)J Clin Psychopharmacol 1993 Dec;13(6):423-8
Treatment of social phobia with clonazepam and placebo.
Davidson JR, Potts N, Richichi E, Krishnan R, Ford SM, Smith R, Wilson WH.
Department of Psychiatry, Duke University Medical Center, Durham, North Carolina 27710.
Clonazepam and placebo were administered in a double-blind pilot study to 75 outpatients with social phobia. The mean maximum dose of clonazepam was 2.4 mg/day at endpoint (range, 0.5 to 3 mg). Treatment was continued for up to 10 weeks. The results of an intent-to-treat analysis indicated superior effects of clonazepam on most measures. Response rates for clonazepam and placebo were 78.3 and 20.0%. Drug effects were apparent on performance and generalized social anxiety, on fear and phobic avoidance, on interpersonal sensitivity, on fears of negative evaluation, and on disability measures. Significant differences were evident by week 1, 2, or 6, depending upon the rating scale used. Clonazepam was well tolerated in general, although unsteadiness and dizziness were more severe and persistent than was the case for placebo subjects.
> im finally tapering off my two AP's and going on Nardil. dam straight. i want to feel and fit in and be able to relax. ive read journal after journal about this med and nothing comes close. i was suppose to do this last month but i chickened out of it because i thought effexor and remeron togehter would kick butt.
> any feedback with success on nardil please answer. or bad feedback.
> ross:)
poster:Rick
thread:92572
URL: http://www.dr-bob.org/babble/20020208/msgs/93296.html