Re: TCA's and BPD-Link? » Elizabeth

Posted by Chloe on January 25, 2002, at 17:15:47

In reply to Re: TCA's and BPD » Chloe, posted by Elizabeth on January 25, 2002, at 0:57:13

> >There have also been some studies and case reports suggesting that TCAs (amitriptyline in particular) can have "paradoxical" effects in depression associated with BPD, making patients feel worse rather than better. I believe that TCAs can worsen symptoms such as self-destructiveness, paranoia, and hostility.
>
> There may be a relationship between BPD symptoms and mixed mania or hypomania in bipolar disorder. Tricyclics are thought to be more likely to trigger or exacerbate dysphoric (mixed) manic states than other ADs, and this may be why they make some borderline patients worse: because dysphoric mania is part of the problem.

Elizabeth,
I just added 20 mgs of Amitriptyline to my cocktail for neuropathic scalp pain. I also take less than 2 mgs of celexa, plus a low dose of neurontin and lithium.
After two weeks on amitriptyline, I am having increased cycling and horrific aggitated mixed states. I have not lost my temper in such abrupt and abusive ways in so long. I am sure it's the amitrip. and asked my pdoc to switch to doxepin. She refused. Saying that all TCA;s are alike. Changing won't make a difference. So she said to decrease the celexa more and see if the cycling stops. But I think it's the Ami...Celexa can make me irritable, but not explosive, hostile and rageful, like I feel on ami...
Anyway, I was hoping you had a link that I could give to her that says Ami is "particularly" bad for the rapid cycling bipolar (ex-BPD, since I have not been self destructive in over a decade..), like me. Any info would be greatly appreciated.
If I just didn't have this dumb scalp pain induced from the lithium, I could just go up on that and I think the cycling would decrease. But without a TCA, the burning is so painful, I can't tolerate the Li...
Many thanks for answering. I really enjoy reading your informative posts.
Chloe

Thread

Are tricylics safer than ssris? borderliner21 1/19/02
...
Re: Are tricylics safer than ssris? borderliner21 1/20/02
Re: Are tricylics safer than ssris? » Mr. Scott spike4848 1/20/02
Re: Are tricylics safer than ssris? » spike4848 Mr. Scott 1/20/02
Re: Are tricylics safer than ssris? » borderliner21 Mr. Scott 1/20/02
Re: Are tricylics safer than ssris? OldSchool 1/20/02
Re: Tricyclics AND SSRI's? » borderliner21 Chloe 1/20/02
Re: Are tricylics safer than ssris? » borderliner21 Elizabeth 1/23/02
Re: Are tricylics safer than ssris? » spike4848 Elizabeth 1/23/02
Re: Are tricylics safer than ssris? » Elizabeth spike4848 1/23/02
Re: TCA's and BPD » Elizabeth Chloe 1/23/02
Re: TCA's and BPD finelinebob 1/24/02
Re: TCA's and BPD » Chloe Elizabeth 1/25/02
Re: TCA's and BPD-Link? » Elizabeth Chloe 1/25/02
Re: TCA's and BPD-Link? » Chloe Ritch 1/26/02
Re: TCA's and BPD-Link? » Ritch Chloe 1/26/02
Re: Depakote and Neurontin-yes » Chloe Ritch 1/26/02
Re: Depakote/Neurontin/Amitrip » Ritch Chloe 1/26/02
Re: Depakote/Neurontin/Amitrip » Chloe Ritch 1/26/02
Re:TCA less likely to cause rage? Chloe 1/27/02
Re:TCA less likely to cause rage? » Chloe Ritch 1/27/02
Re:TCA less likely to cause rage? » Ritch Chloe 1/28/02
Re:TCA less likely to cause rage? » Chloe Ritch 1/28/02
Re:TCA less likely to cause rage? » Ritch Chloe 1/28/02
Re:TCA the answer » Ritch Chloe 1/28/02
Re:TCA less likely to cause rage? » Chloe Ritch 1/28/02
...
try the 20mg amitrip..good luck (nm) Ritch 2/8/02

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