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Re: Levodopa as an augmentation strategy ?!

Posted by ben on January 24, 2002, at 2:45:25

In reply to Re: Levodopa as an augmentation strategy ?! » ben, posted by TSA West on January 24, 2002, at 1:55:10

Hi TSA

I tried Venlafaxine more than a year ago up to 150 mg. I had allways headaches, was hungry (weight gain) and was awfully sweating. I tokk it to 20-40 mg Seropram and thats perhaps the clou why I had more side effects ?! Perhaps I should give it a try alone ?! But i think sticking to Moclobemide could be worth either because improvement does take often more than 2 or 3 weeks with ADs in general. I read esp. of Moclobemide that mood improvements do kick in often after 4 weeks, first you feel only more energized (could lead to agitation, anxiety, sleep probs...). I didnt try Serzone (Nefazodone) because I got sedation of all ADs with a sedating potential (Remeron kocked me out, as well as Surmontil) This summer I tried Zyprexa as a adjunct. Took only 1.25 mg at night and was knocked out for next day (dizziness, fatigue, sleepy...). What about Prozac (Fluoxetine) ? I would try it but I am afraid of side effects and the long wash out if it doesnt work !

> Greetings Ben,
>
> Buproprion (Wellbutrin) would be a novel choice for you due to its stimulating properties and reuptake inhibition of dopamine.
>
> I was thinking you could also try venlafaxine (Effexor) because there is no known dopamine depletion with it and it may inhibit the reuptake of dopamine at high doses. Some people report stimulation from it; others do not.
>
> If all your doctor determines that you can try is an anti-RLS drug then consider Mirapex (pramipexole), which has studies done on it for major depression and bipolar depression.
>
> Good luck Ben,
> tSa WeSt


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