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Re: Inderal

Posted by djmmm on January 15, 2002, at 17:25:34

In reply to Inderal, posted by Rakken on January 10, 2002, at 15:45:23

> I hear that beta blockers like propanolol decrease the amount of bloodpumped to the heart each revolution. It doesn't sound very healthy or safe for your body or cardiovascular system. The reason I ask, is I'm considering giving it a try for aiding anxiety. I haven't heard of an instance where it hasn't helped in that area. What possible side effects are there? And are there any irreversible long term effects from it? I take Adderall and clonidine currently. How fast does it take to work and is it that noticeably helpful? How good does it work? Would it be more effective than say klonopin or ativan? Thanks in advance!


ok..here is the low down on Inderal (Propanolol)...I have been taking it for 1.5 years, for a tremor in my hand and social phobia, and for what its's worth, I think it's fabulous.

Inderal is a non-selective beta-blocker..it blocks both alpha and beta receptors in the heart and vascular smooth muscle. What is unique about Inderal is that it is a œ-adrenergic antagonist that competes with neutotransmitters (passes blood brain barrier)


in english:
in the heart: blocking œA-receptor= decrease heart rate, cardiac output, blood pressure

Inderal stops your "fight or flight" response...the feeling you get when someone scares you or when you are speaking in public,etc.

it is a perfectly safe drug, and actually very good for your heart, it decreases the workload on your heart, allowing it to slow down a bit (like from a sprint to a jog)

..and it blocks the norepinephrine receptors in your brain, acting as an antagonist(fits in receptor, but does not exert any effect)

...so, under normal conditions (anxiety), as norepinephrine is released and binds to the receptors, that "connection" = anxiety

with Inderal blocking those receptors, no "connection" is made = no anxiety


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