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dopamine » Geno

Posted by CalvaryHill on January 11, 2002, at 20:31:25

In reply to Re: increased saliva, posted by Geno on January 11, 2002, at 16:52:23

You're right, it affects GABA mainly, but also dopamine to some extent:

Laboratory of Behavioral Pharmacology, Novo Nordisk A/S, Bagsvaerd, Denmark. "Characterization of tiagabine (NO-328), a new potent and selective GABA uptake inhibitor." European Journal of Pharmacology. 196(3):257-66, 1991 Apr 24:

"In a manner similar to other anti-epileptic drugs, tiagabine potentiated dopaminergic function (methylphenidate-induced gnawing in mice) although it did not substitute for amphetamine in amphetamine-trained animals."


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