Posted by JohnX2 on December 10, 2001, at 15:32:14
In reply to Zanaflex follow up., posted by JohnX2 on December 3, 2001, at 7:34:25
I've given up on Zanaflex for the time being
because the 1/2 life is just way to short to
make the dosing manageable. But I believe its
partial alpha-2 agonism makes it a useful
noradrenergic "buffer" medication and may be
helful as an adjunct in TRD associated with
response followed by poop out.There is a sustained released version in
Europe called "Sirdalud" that I am investigating.-john
>
> 2.5 days so far. Zanaflex (tizanidine) is similar
> to clonodine.
>
> My dose was supposed to be 4 mg at night
> and 2 mg in the morning. But I've changed it
> to 2 mg every 3 hrs. LOL.
>
> At first it totally wiped me out, but I've
> grown tolerant to the drowsiness and I have
> substantially reduced my Klonopin dose because
> I'm running low. But the Zanaflex seems to be
> completely curing my headache and by
> now with the klonopin drop off I normally would
> be cussing and throwing stuff and wanting to
> kill myself, but I'm actually in no pain and
> just a hair nervous. slight dry mouth too.
>
> -john
poster:JohnX2
thread:85853
URL: http://www.dr-bob.org/babble/20011202/msgs/86488.html