Posted by JohnX2 on November 18, 2001, at 16:19:54
In reply to Atypical a.d's make Endogenous depression worse?, posted by jay on November 15, 2001, at 0:59:18
I was thinking about trying nortriptyline.What would I expect from the side effects of
these older tricyclics vs the new meds?I tend to do better on stimulating meds.
They usually don't make me anxious or jittery
and are more likely to lift my depression.
The sedating meds like Paxil are disasterous.
While Zoloft and Wellbutrin were great.Anyways, I haven't found a "majic bullet" that
sticks. I always get an elesuve anti-depressant
response and was wondering what some of these
older NRIs do in the brain that is different
from meds like Wellbutrin or Effexor or Reboxetine?One of those older meds is supposed to be
good for tension headaches, I don't remember
which, but it was a noradrenergic med and I
get tension headaches from meds.thanks for any info,
john>
> There is much talk about how the tricyclics somehow aren't good for "atypical" depression. I think, though, that most folks have a number of symptoms that do somewhat indicate atypical depression, but also have many endogenous symptoms. (Irritability, anxiety, bouts of insomnia..etc.) I also think the reverse of the first statement is true...and that meds for atypical depression can are little to no-good for endogenous depression symptoms, and maybe can make them worse, especially in the long run.
>
> From my little bit of experience (n=1..heh,) it seems the highly activating quality of the newer SRI/SNRI's seem to really complicate endogenous depressive symptoms. I think that is why many only attain partial relief from the newer a.d's. I've noticed that the tricyclics, in particular nortriptyline, help my depression and anxiety in a fairly different way than the newer meds.
>
> Again, this is why I believe folks should consider (especially if you have had many problems with the newer a.d.'s..or they haven't helped.) a tricyclic. Two of the more popular ones seem to be desipramine and nortriptyline. As far as side-effects go...some are different than the newer meds, but I don't think much worse in the long-term. Weight-gain is not much different, from what long-term experience seems to show.
>
> There are a vast number ot tricyclics to try...so I would suggest taking a shot.
>
> Jay
poster:JohnX2
thread:84318
URL: http://www.dr-bob.org/babble/20011113/msgs/84588.html