Posted by Mark H. on November 15, 2001, at 21:14:55
In reply to Re: What is the highest dose taken of effexor 375mg. » THE_CROW, posted by Pamela Lynn on November 14, 2001, at 14:35:43
I too was up to 450 a day at the end of the first year I took Effexor, at which time I was having withdrawal symptoms within 4-6 HOURS after my last dose (ringing in my ears, head swimming, perceptual disturbances). Increasing my dosage simply didn't work. It took weeks for me to get off of it, and after quitting completely, I had flu symptoms for another 6 weeks. My experience, unfortunately, is apparently not that uncommon.
What finally worked sometime later was a combination of medications that potentiate the Effexor I take, making its effect in my body stronger with fewer of the unpleasant side effects and no need for an ever-increasing dosage. I have been on regular (not XR) Effexor, 150mg once a day (after breakfast) for over 3 years, and it is still highly effective.
However, each person's body is a little different; it's important to work with your doctor to find out what is right for you.
The other meds I take are Cytomel, Pindolol and either methylphenidate or (for the past 3 months) ProVigil.
The last time I looked, the manufacturer's highest recommended in-patient dosage for Effexor was still 375mg a day. However, this does not mean that it is inappropriate for an out-patient to go higher under medical supervision; it simply means that the manufacturer has not done controlled tests on subjects above 375mg a day.
Best wishes,
Mark H.
poster:Mark H.
thread:84248
URL: http://www.dr-bob.org/babble/20011113/msgs/84367.html