Posted by JohnX2 on November 13, 2001, at 15:08:01
In reply to Re: Info on Remeron, posted by tensor on November 13, 2001, at 14:59:59
It affects serotonin in a few ways:- it blocks a serotonin receptor that causes
anxiety (the 5-ht2 family)- there is an indirect interaction with
a norepinpehrine path which can "accelerate"
serotonin firing in an area of the brain.
This can cause a bit of the anxiety, but
also offset the tiredness and improve the
depression symptoms.The SSRI meds block the re-uptake of serotonin
so are working in a tottally different manner.This is what makes Remeron such a unique med.
They have derivatives of Remeron in research
that I read about that remove the anti-histamine
sedation property and would make it potentially
more of a "clean" anti-depressant.-john
> How long have you been taking Remeron? Remeron helped my depression, if you don't respond to 30mg I think you/your pdoc should raise the dosage. You will notice when dose is too high. I can only talk for myself but a too high dosage makes me stressed and anxious. It is said to affect serotonin, but that doesn't seem to be the case for me.
poster:JohnX2
thread:84092
URL: http://www.dr-bob.org/babble/20011113/msgs/84100.html