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Re: klonopin......PaulB

Posted by PaulB on November 12, 2001, at 12:43:53

In reply to Re: klonopin......PaulB, posted by Thrud on November 11, 2001, at 4:33:16


>Hi Paul,
>
> That's pretty interesting. How does Xanax differ in its mode of operation compared to Klonopin (Rivotril)? Xanax is supposed to be somewhat of an antidepressant: I presume it interacts with seratonin receptors somehow as well?
> With regards to Klonopin being an anticonvulsant, I happen to be taking Lamictal as well as Xanax...but for its AD, not AC properties, so I doubt I could simply trade my Lamictal+Xanax combo in for Klonopin alone.
>

> BTW I read somewhere that Xanax is not available in the UK? If that is true you are missing out on a very effective anxiolytic (if very short acting).
>
> Thanks.
>
> Thrud

Xanax is very similar to Klonopin, the major difference being the longer half-life with the former. Xanax may exert ad effects by stimulating the release of norepinephrine indirectly because of its agonism at the bz site,i.e. it may decrease serotonin firing but consequently increase norepinephrine firing rate and turnover.
Perhaps Klonopin and Lamictal is worth a try. You would get a longer duration of anxiety relief with Klonopin and you could still use Lamictal for its AD effect if there were no known drug-drug interactions beytween the two.
PaulB


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