Posted by SLS on November 9, 2001, at 12:59:23
In reply to Re: Refractary bipolar depression To Scott !!!, posted by jazzdog on November 9, 2001, at 11:23:35
> >
> > I heard about this topomax + lamictal combo
> > and am also very curious. Seems they work
> > orhoganally, one focusing on NMDA (lamictal) and
> > the other AMPA and GABAa.
>
> Hi John - I'm just learning a bit about brain chemistry, so forgive the naive questions. Is lamictal an NMDA receptor agonist? Is that why it works to enhance cognition and treat depersonalization / derealization? I've just started a tiny dose of lamictal - 6.5 mg to tritrate slowly up to 150 + - along with 50 mg sertraline to treat my derealization and poor cognition. I've also got lifelong depression, so any help there will be good too. The thing is, I could swear that my head cleared for about half an hour the first day I took it. Is this possible on such a tiny dose, or am I imagining things? I'm usually pretty good at self-assessment for drug reactions, so I'm hoping it's the former. Lamictal is the only treatment so far for chronic derealization, and I so badly want to escape this waking dream. Thanks - Jane
Hi Jane.Have you ever tried Zyprexa?
Just curious.
- Scott
poster:SLS
thread:83508
URL: http://www.dr-bob.org/babble/20011104/msgs/83673.html