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Re: neurodex » SLS

Posted by JohnX2 on November 6, 2001, at 23:13:35

In reply to Re: neurodex, posted by SLS on November 6, 2001, at 13:21:45


I have the german- >english translated memantine
pdr if you are interested, it didn't list too
many interactions accept with other drugs
like baclofen, and anti-parkinson drugs.
Suggested possible kidney complications.
Unfortunately it didn't show detailed information
about the metabolism. That other link I posted
from a research supplier of memantine had more
information about the medicine in clinical trials,etc.

I found out the hard way not to take dxm with
an maoi. Really goofed up my system.

The adjunctive med to dxm was quinidine and
required only about 1/30-1/40 the therapeutic dose
of quindine for heart related problems to
achieve the enzyme inhibition. Alpha-2 and
GabaA agonists protect against nmda hypoactivity
induced neurotoxicity. I was thinking it might
be novel to try a combo of dxm,quinindine,tenex,
and adderall. A lot of the information I described
is covered in detail in patents I discovered
about nmda antagonists, if you set up an email
accnt, I'll forward the information.

-john

> > Interesting. How long do you think I'd have to fake chronic cough for to be admitted into the trails? jk ;-)
> >
> > I say its a great idea provided that it comes out cheaper than memantine (and given that its just a combination of 2 already widely used drugs I would imagine it would be cheaper). After reading through some of those patents its a wonder why someone didn't do this a long time ago.
>
>
> Hi guys.
>
> Thanks for all the great info!
>
> What enzyme inhibitor do you think they use?
>
> Overall, how would you compare dextromethorphan with memantine - efficacy, side effects, drug interactions, toxicity...? Can memantine be used with an MAOI?
>
> Thanks.
>
>
> - Scott


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poster:JohnX2 thread:83233
URL: http://www.dr-bob.org/babble/20011104/msgs/83401.html